Antibiotics X-14889 A, C and D

Details Antibiotics X-14889 A, C and D Antibiotics X-14889 A, C and D

Filed on

1983-11-23

Date issued

1985-08-27

Examiner

Brown, Johnnie R.

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Carbohydrates or derivatives

Other Related Categories

536 168, 536 41, C07H 300

Type

Patent

Status

active

Patent number

045379564

Description

ABSTRACT:
There is presented antibiotic compounds designated as Antibiotics X-14889 A, C and D of the formulas ##STR1## wherein (for X-14889A) R.sub.1 is methyl, R.sub.2 is methyl, R.sub.3 is hydrogen, R.sub.4 is methyl and R.sub.5 is hydrogen or (for X-14889C) R.sub.1 is hydrogen, R.sub.2 is methyl, R.sub.3 is hydrogen, R.sub.4 is methyl and R.sub.5 is CO.sub.2 H or ##STR2## and the pharmaceutically acceptable salts thereof. The compounds exhibit antimicrobial activity and one of the compounds X-14889C also exhibits activity against Treponema hyodysenteriae (in vitro), Plasmodium berghei and as food efficiency enhancers in ruminants.
Also presented is a process to produce the above compounds and another known component Antibiotic X-14889B.

REFERENCES:
patent: 4161520 (1979-07-01), Osborne et al.
patent: 4174404 (1979-11-01), Nakatsukasa et al.

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