Chemistry of carbon compounds – Miscellaneous organic carbon compounds
Patent
1973-01-26
1976-04-27
Cockeram, H. S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
252182, 260 25AD, 260 775AP, 260859R, 424 78, C08G 1848, A61K 31785
Patent
active
039534065
ABSTRACT:
This application discloses lightly cross-linked, swellable polymers including both oleophilic and hydrophilic chains. The polymers have an unusually high capacity for absorbing from solution large organic molecules containing polar groups. The polymers are free of components leachable in the gastrointestinal tract, have low oral toxicity and dermal sensitivity and can be utilized in vitro or in vivo to absorb lipids from bile. The polymers have exhibited absorption as high as 309% total and 59% solids from a concentrated micellar bile. Cholesterol, lecithin and sodium cholate were confirmed in the absorbate by thin-layer chromotography.
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California Institute of Technology
Cockeram H. S.
Jacobs Marvin E.
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