Imidazole derivatives for treating joint diseases and Wilson's d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548342, 548344, A61K 31415

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active

046123245

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 each individually is hydrogen, or lower alkyl and R.sup.4 is hydroxy, lower alkoxy, aryl-(lower alkoxy), amino, mono(lower alkyl)amino or di(lower alkyl) amino,
and pharmaceutically acceptable salts thereof which are useful in the treatment of degenerative joint diseases and of Wilson's disease are described.

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Chemical Abstracts, 74:100398g (1971) [Felix, A., et al., Org. Prep. Proced. 1970, 2(4), 255-8].
Trout, G., J. Med. Chem., 1972, 15(12), 1259-61.
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