Novel racemization process

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07C12175

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active

041511956

ABSTRACT:
A process for the preparation of an ester of chiral (A) acid with a racemic (R,S) .alpha.-cyano-3-phenoxybenzyl alcohol (B) by reacting an ester of chiral (A) acid with .alpha.-cyano-3-phenoxybenzyl alcohol of the formula ##STR1## in its optically active (R) form or (S) form or a mixture of esters of said (R) alcohol and (S) alcohol in non-equimolecular proportions with a base selected from the group consisting of ammonia, primary, secondary and tertiary amines, quaternary ammonium compounds, liquid amines of high molecular weight and a catalytic amount of a strong base in at least one solvent for the starting esters and in which the ester of racemic alcohol is soluble and recovering from the resulting solution the ester of chiral (A) acid with racemic (R,S) alcohol.

REFERENCES:
patent: 3046299 (1962-07-01), Julia
patent: 3786070 (1974-01-01), Martel et al.
patent: 3906026 (1975-09-01), Nagase et al.

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