Process for the production of human lysozyme

Details Process for the production of human lysozyme Process for the production of human lysozyme

1991-04-11

1996-12-17

Guzo, David

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 691, 435 697, 435 698, 4351721, 4351723, 4352541, 43525411, 4352542, 43525421, 4352551, 4352552, 43525521, 4353201, 536 231, 536 234, 536 235, C12N 936, C12N 500

Patent

active

055852572

ABSTRACT:
Yeast cells whose DNA has been appropriately engineered to produce and to secrete lysozyme under control of a regulatable promoter are grown in the substantial absence of lysozyme synthesis and then are induced to produce and to secrete lysozyme under growth-limited conditions. This process is particularly suitable for the production of human lysozyme or mutants thereof.

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Cousens et al. (1987), "High level of expression in yeast," Gene, vol. 61, pp. 265-275.

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