Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-03-01
1991-08-06
Ceperley, Mary E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548504, A61K 3140, C07D20916
Patent
active
050378457
ABSTRACT:
A compound of formula (I) ##STR1## and its physiologically acceptable salts and solvates are described as useful in treating and/or preventing pain resulting from dilatation of the cranial vasculature in particular migraine.
The compound (I) may be prepared, for example, by cyclizing a compound of formula (II) ##STR2##
REFERENCES:
patent: 3322787 (1967-05-01), Sletzinger et al.
patent: 3624103 (1971-11-01), De Martus et al.
patent: 4283410 (1981-08-01), Schut et al.
patent: 4816470 (1989-03-01), Dowle et al.
M. Dorole et al., Chem. Abst., vol. 100, No. 103175y (1983).
Ceperley Mary E.
Glaxo Group Limited
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