Pyridine-2,4-and -2,5-dicarboxylic acid amides and medicaments b

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514355, 546316, 546323, A61K 3144, C07D21381, C07D21382

Patent

active

050378392

ABSTRACT:
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X have the meanings given, a process for the preparation of these compounds and their use, in particular in medicaments for influencing the metabolism of collagen and collagne-like substances or the biosynthesis of Cl.sub.q.

REFERENCES:
patent: 2852519 (1958-09-01), Kruse
Samejima, Yakugaku Zashi, vol. 80, pp. 1706-1712 (1960); Chem. Abstracts, vol. 55, 10439-10440e (1961).
Talma et al., "Reductions of Activated Carbonyl Compounds with Chiral Bridged 1,4-Dihydropyridines. An Investigation of Scope and Structural Effects", Journal of the American Chemical Society, vol. 107, pp. 3981-3997 (1985).
Thunus et al., "Preparation Des Monesters Des Acides Pyridine Dicarboxyliques", Journal De Pharmacie De Belgique, pp. 3-21, 1968.
Dewar et al., "Effect of Structure on the Stability of Nematic Mesophases",: J. Amer. Chem. Soc. 97 (23), pp. 733-741.
Wolfensberger, et al., "Identification of Quinolinic Acid in Rat and Human Brain Tissue", Neuroscience Letters, vol. 41, pp. 247-252 (1983).
Meyer, 19 Chemical Abstracts, 2953-54 (1925).
Ustavshchikov et al., 58 Chemical Abstracts 2431e (1963).
Nesterova et al., 87 Chemical Abstracts 90773c (1977).
Organikum, Organisch Chemisches Grudpraktikum, VEB Deutscher Verlag der Wissenschaften, pp. 255-256 (15th ed., 1976).
A. Hubbuch, Schutzgruppen in der Peptidsynthese (Teil 1): Schutzgruppentaktik, Amino-und Carboxyl-Schutzgruppen, Kontakte, 3/79, pp. 15 & 19, et seq.
Houben-Weyl, Methoden der Organischen Chemie (Methods of Organic Chemistry), vol. E5, pp. 496-504, 4th Ed., 1985.
J. Org. Chem., vol. 39, No. 8 (1974), p. 1158.
Elke Langhals et al., "Eine einfache neue Synthese der Fusarinsaure und anderer 5-Alkyl-2-pyridincarbonsauren", No. 5, Liebigs Ann. Chem., pp. 930-949 (1982).

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