Isotopic tracer composition and method for making and using same

Details Isotopic tracer composition and method for making and using same Isotopic tracer composition and method for making and using same

1995-05-30

1997-08-26

Kight, John

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

534 10, 534 14, 424 149, 424 153, 424 157, 424 169, A61K 5108, A61K 5110, A61K 5104

Patent

active

056608110

ABSTRACT:
An isotopic tracer composition and methods of making and using same for radiological evaluation of body functions and diseases in a subject and for radiological therapy. The isotopic tracer composition comprises a protein carrier agent such as fibrinogen, antibodies, enzymes or portions thereof, bound to a radioisotope which has been reduced to a lower oxidation state by stannous phosphate at a pH of greater than 7. Some suitable radioisotopes are isotopes of technetium, rhenium and ruthenium.

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