Drug effect-enhancing agent for antitumor drug

Details Drug effect-enhancing agent for antitumor drug Drug effect-enhancing agent for antitumor drug

1993-05-07

1994-04-19

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514 89, 514 90, A61K 3144, A61K 3155, A61K 31535, A61K 31675

Patent

active

053045505

ABSTRACT:
Compounds of the formula (I): ##STR1## in which the nitrogen-containing hetero ring portion is 1,4-dihydropyridine ring or a pyridine ring, R.sup.1 is only present when the nitrogen-containing hetero ring is a 1,4-dihydropyridine ring, and Z is a group of the formula (II): ##STR2## in which R.sup.4 and R.sup.5 may be the same or different and together may form one divalent group, are effective agents for enhancing the antitumor effect of antitumor drugs.

REFERENCES:
Kamiwatari, Mikio, Chemical Abstract 113:34417h (1990); from Kagoshima Daigaku Igaku Zasshi 41(3), (1989), pp. 225-234.

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