Process for preparing polychlorobenzamide derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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71118, 424324, 260 459NC, 260558D, 260559S, C07C10208

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active

040228304

ABSTRACT:
A novel process for preparing polychlorobenzamide derivatives, useful as biocidal agents, flame retardants in plastic resins, and the like, from corresponding polychlorobenzonitrile compound in near quantitative yields is disclosed. A polychlorobenzonitrile compound is admixed and reacted with excess sulfuric acid at an elevated temperature e.g. 100.degree. to 160.degree. C for a time period sufficient to hydrolyze the polychlorobenzonitrile derivative to the corresponding polychlorobenzamide derivative. The reaction product is then recovered to provide the corresponding polychlorobenzamide derivative in an excellent yield above about 90%.

REFERENCES:
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Sudborough et al., S. Chem. Soc. (London), vol. 71, pp. 229-234 (1897).
Sudborough, S. Chem. Soc. (London), vol. 67, pp. 601-604 (1895).
Montagne, Rec. Trav. Chim. vol. 21, pp. 385-386 (1902).
Reich, Bull. Chem. Soc. France, vol. 21, pp. 217-223 (1917).
Griffiths et al., Biochem. J., vol. 98, pp. 770-771 (1966).
Birchall et al., J. Chem. Soc., Part C, 1971, pp. 1343-1348.

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