Nucleosidic phosphorylating agent and methods

Details Nucleosidic phosphorylating agent and methods Nucleosidic phosphorylating agent and methods

1981-08-20

1983-07-12

Love, Ethel G.

Chemistry of carbon compounds

Dipeptides, e.g., aspartame, anserine, carnosine, etc.

C07F 902

Patent

active

043930107

ABSTRACT:
Compounds of the formula ##STR1## where R is a base labile substituted-phenyloxy protecting group, are useful as phosphorylating reagents in the synthesis of oligonucleotides by a phosphotriester method.

REFERENCES:
Crea et al., Proc. Natl. Acad. Sci. USA, 73(12) pp. 5765-5769, Dec. 1978.
Khorana, Federation Proceedings (American Society of Biological Chemists) 19(4), pp. 931-934, Dec. 1960.

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