Substituted imidazole phosphonic and phosphinic acid derivatives

Details Substituted imidazole phosphonic and phosphinic acid derivatives Substituted imidazole phosphonic and phosphinic acid derivatives

1992-03-10

1993-05-04

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514326, 514396, 514397, 514398, 514399, 514400, 544139, 544337, 546 22, 548111, 548112, A61K 31535, A61K 31415, C07D41314, C07F 928

Patent

active

052082342

ABSTRACT:
Novel compounds having the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined herein. These compounds inhibit the action of angiotensin II and are useful, therefore, for example, as antihypertensive agents.

REFERENCES:
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4355040 (1982-10-01), Furukawa et al.
patent: 4582847 (1986-04-01), Furukawa et al.
patent: 4820843 (1989-04-01), Aldrich et al.
patent: 4870186 (1989-09-01), Aldrich et al.
patent: 4874867 (1989-10-01), Aldrich et al.
patent: 4880804 (1989-11-01), Carini et al.

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