Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1993-12-17
1997-02-25
Ulm, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530358, 435 691, 4352523, 4353201, 536 235, C07K 14705
Patent
active
056060211
ABSTRACT:
The present invention provides recombinant proteins having the hormone-binding and/or transcription-activating characteristics of a mineralocorticoid receptor. The invention also provides proteins expressed from recombinant DNA encoding a naturally occurring receptor having the hormone-binding and/or transcription-activating characteristics of a mineralocorticoid receptor.
REFERENCES:
Biochemistry 15(19):4298-4304 (1976) Atger et al. Chromatographic Separation and Phosphocellulose of Activated and Nonactivated Forms of Steroid . . . .
J. Biol. Chem. 262 (17) 8121-7 (15 Jun. 1987) Lombes et al. A New Affinity Matrix for Mineralocorticoid Receptors.
Science 237: 268-275 (17 Jul. 1987) Arriza et al. Cloning of Human Mineralocorticoid Receptor Complementary DNA. Structural and Functional Kinship . . . .
Arriza Jeffrey
Evans Ronald M.
Giguere Vincent
Ong Estelita S.
Thompson Catherine C.
Reiter Stephen E.
The Salk Institute for Biological Studies
Ulm John
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