Thiol-derivatized nucleosides

Details Thiol-derivatized nucleosides Thiol-derivatized nucleosides

1993-09-03

1996-11-26

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 276, 536 278, 536 2781, 536 281, 536 284, 536 285, 536 2853, 536 2854, 536 553, C07H 1906, C07H 1916, C07H 2100

Patent

active

055787185

ABSTRACT:
Nucleosides and linked nucleosides functionalized to include alkylthiol chemical functionality at ribofuranosyl positions, nucleosidic base positions, or on internucleoside linkages. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleosides through the alkylthio group.

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