Method for treating herpes viral infections using benzothiophene

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 3144

Patent

active

055786154

ABSTRACT:
Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R.sup.1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.

REFERENCES:
patent: 3933827 (1976-01-01), Brossi et al.
patent: 4018780 (1977-04-01), Lappi et al.
patent: 4045565 (1977-08-01), Le Pecq et al.
patent: 4310667 (1982-01-01), Le Pecq et al.
patent: 4334070 (1982-06-01), Berger et al.
patent: 4483989 (1984-11-01), Le Pecq et al.
patent: 4851417 (1989-07-01), Archer
patent: 4897398 (1990-01-01), Gros et al.
Cheng et al. (1983) "Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1" Proc. Natl. Acad. Sci. USA 80:2767 -2770.
Duke et al. (1986) "In vitro and in vivo activities of phosphate derivatives of 9-(1,3-dihydroxy-2-propoxymethyl guanine against cytomegaloviruses" Antiviral Research 6:299-308.
Shafiee et al. CA 84(25):180104C 1976.
Shafiee et al. (1976) "Photochemical synthesis of [1]benzothieno[3,2-h]isoquinoline" J. Heterocyclic Chem.13(1):141-144.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for treating herpes viral infections using benzothiophene does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for treating herpes viral infections using benzothiophene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating herpes viral infections using benzothiophene will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1973456

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.