Derivatives of physostigmine, their use and pharmaceutical formu

Details Derivatives of physostigmine, their use and pharmaceutical formu Derivatives of physostigmine, their use and pharmaceutical formu

1993-01-11

1994-05-24

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548429, 424443, 424449, C07D48700, A61K 3140

Patent

active

053149068

ABSTRACT:
The therapeutic use of new salts of physostigmine in the treatment of syndromes related to changes in cerebral metabolism in the elderly is described. The new salts of physostigmine, which are based on phosphatidic acid, are highly lipophilic and exhibit excellent bioavailability when administered orally, transcutaneously or transepidermally.

REFERENCES:
patent: 4978673 (1990-12-01), Merone et al.

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