Process for converting lipid-containing bacterial capsular polys

Details Process for converting lipid-containing bacterial capsular polys Process for converting lipid-containing bacterial capsular polys

1992-07-13

1994-05-24

Griffin, Ronald W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435170, 435262, 435280, 536117, 5361231, 424 88, 424 92, 210601, 210616, 210631, C12P 1904, C12P 104, C12R 121

Patent

active

053148118

ABSTRACT:
A process for converting lipid-containing bacterial capsular polysaccharide, such as lipo-polyribosyl ribitol phosphate, lipo-PRP, into lipid-free, endotoxin-free polysaccharide, such as polyribosyl ribitol phosphate, PRP, by solubilizing polysaccharide-containing powder derived from culture media of bacteria, such as Haemophilus influenzae type b, cleaving covalently bound fatty acids from the polysaccharide, and removing the lipids, and endotoxin.

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