Surgery – Means for introducing or removing material from body for... – Treating material applied to or removed from external...
Patent
1991-04-26
1993-05-04
Waddell, Frederick E.
Surgery
Means for introducing or removing material from body for...
Treating material applied to or removed from external...
604294, A61M 3500
Patent
active
052076601
ABSTRACT:
Therapeutic compositions are administered to the ocular tissues by positioning a balloon catheter having an illuminating fiberoptic stylette therein in the retrobulbar or parabulbar space of a patient. After the catheter is properly positioned, the composition is sequentially injected at predetermined intervals over a period of time. A variety of compositions can be administered including corticosteroids, antibiotics, macular degeneration alleviating compositions and inflammation alleviating compositions. Such administration of the therapeutic composition sustains appropriate levels of the composition in the ocular tissues without inducing toxic effects in unaffected tissues.
REFERENCES:
patent: 3788327 (1974-01-01), Donowitz et al.
patent: 3954110 (1976-05-01), Hutchison
patent: 4299227 (1981-11-01), Lincoff
patent: 4454151 (1984-06-01), Waterbury
patent: 4820270 (1989-04-01), Hardcastle et al.
Clinical Ophthalmology, vol. 4, Chap. 43, "Nonspecific Treatment of Uveitis" T. F. Schlaegel, Jr., pp. 1-13, (1988).
Arch Ophthal-Vol. 83, May 1970, "Orbital Infusion of Steroids in the Rabbit", Norman D. Levine et al., pp. 599-607.
Reprinted from Ophthalmology, American Academy of Ophthalmology, Apr. 1979, "A Temporary Balloon Buckle for the Treatment of Small Retinal Detachments", Harvey A. Lincoff, et al., pp. 586-592.
Arch Ophthalmol-Vol. 108, Apr. 1990, "A Fiberoptic Stylette for Localizing the Balloon Buckle" Harvey Lincoff, et al., p. 607.
Dept. of Ophthalmol, School of Med., Tottori Univ. 86, 75, Dexamethasone, "Studies on the Intraocular Penetration of Dexamethasone after Subcojunctivel or Retrobulbar Injection in Rabbits", N. Ichigashira, pp. 1453, 1455, 1457, 1459 and 1460.
Am. Journal of Ophthalmology, vol. 62, No. 4, Oct. 1966, "Restoration of Vision in Temporal Arteritis by Retrobulbar Injections of Steroids", Robert A. Schimek, et al., pp. 693-696.
J. Neurosurg. 63:806-810, 1985, "Current application of `high-dose` Steroid Therapy for CNS Injury--A pharmacological perspective", J. Mark Braughler, et al.
Am. Journal of Ophthalmology 110:665-669, Dec., 1990, "Treatment of Traumatic Optic Neuropathy With Corticosteroids", Thomas C. Spoor, et al.
Arch Ophthal-Vol. 80, Oct. 1968, "Radioactive Depot-Corticosteroid Penetration into Monkey Ocular Tissue", Robert A. Hyndiuk, M.D. et al., pp. 499-503.
Investigative Ophthalmology, vol. 4, No. 3, "An autoradiographic study of the penetration of subconjunctivally injected hydrocortisone into the normal and inflamed rabbit eye", H. J. McCartney, et al., pp. 297-302, (1965).
Am. Journal of Ophthalmology 103:281-288, Mar., 1987, "Echographic Localization of Corticosteroids After Periocular Injection", William R. Freeman, et al.
Arch. Ophthal-vol. 79, Jun. 1968, "Patterns in Experimental Uveitis", Samuel B. Aronson, pp. 763-767.
Ophthalmology, May 1988, vol. 95, No. 5, "Ocular Complications Associated With Retrobulbar Injection", Craig M. Morgan, et al., pp. 660-665.
Am. Journal of Ophthalmology 92:245-251, 1981, "Results with a Temporary Balloon Buckle for the Repair of Retinal Detachment", Harvey Lincoff, et al.
J. of Royal Society of Medicine, vol. 84, 1991, "Prospects for the Treatment of Multiple Sclerosis", Richard A. C. Hughes, pp. 63 and 64.
Cornell Research Foundation Inc.
Fay Zohreh A.
Waddell Frederick E.
LandOfFree
Method for the delivery of compositions to the ocular tissues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for the delivery of compositions to the ocular tissues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the delivery of compositions to the ocular tissues will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1971786