Process for defibrillation pretreatment of a heart

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

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A61N 139

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053144481

ABSTRACT:
The present invention is a process to apply an electrical pretreatment to a fibrillating heart that begins the process of organizing the action of the chaotically contracting myocardial cells, so that the defibrillating waveform applied after the pretreatment can accomplish its task with less energy than would otherwise be required. The same electrodes are employed for both pretreatment and defibrillation. In one preferred embodiment a long-duration, low-voltage pretreatment pulse is generated directly by battery and voltage-conversion circuitry, and is followed by the defibrillation pulse delivered from the previously charged capacitor. In variations on this embodiment, the capacitor is charged during the pretreatment pulse, or between the pretreatment and defibrillation pulses. In other preferred embodiments, pretreatment consists of a train of pulses of appreciably lower energy than the defibrillation pulse, and with inter-pulse time adjusted so that necessary capacitor recharging can be accomplished, so that the same capacitor (a component of dominant size) can be used for all pretreatment pulses and for the defibrillation pulse as well. Wide-ranging variations of pulse duration, height spacing and waveform are included, as well as selected polarity inversions.

REFERENCES:
patent: 4637397 (1987-01-01), Jones et al.
J L Prevost and F Batelli, "Sur quelques effets des descharges electriques sur le couer des mammifers," Comptes rendus hebdomadaires des seances de l'Academie des sciences, vol. 129, pp. 1267, 1899.
R A Winkle, R H Mead, M A Ruder, et al., "Long-term outcome with the implantable cardioverter-defibrillator," J. am Coll Cardiol., vol. 13, pp. 1353-1989.
M H Lehman, S Saksena, "Implantable cardioverter-defibrillators in cardiovascular practice: Report of the policy conference of the North American Society of Pacing and Electrophysiology," PACE, vol. 14, pp. 969-979, Jun. 1991.
R A Winkle, "State-of-the-Art of the AICD," PACE, vol. 14, pp. 961-966, May 1991 pt II.
N G Tullo, S Saksena, R B Krol, "Technological improvements in future implantable defibrillators,"]CARDIO, vol. , pp. 107-111, May 1990.
D P Zipes, J Fischer, R M King, et al, "Termination of ventricular fibrillation in dogs by depolarizing a critical amount of myocardium," Am J Cardiol., vol. 36, pp. 37-44, Jul. 1975.
P S Chen, N Shibata, E G Dixon, et al, "Comparison of the defibrillation threshold and the upper limit of ventricular vulnerability," Circulation, vol. 73 #5, pp. 102-1028, May 1986.
J E Skinner, C Carpeggiani, C E Landisman, et al., "Correlation dimension of heartbeat interval is reduced in conscious pigs by myocardial ischemia," Circ. Res. vol. 68, pp. 966-976, Apr. 1991.
M W Kroll and K W Fulton, "Slope filtered correlation dimension algorithm and its evaluation with pre-fibrillation heart rate data," J Electrocardiology, in press.
E G Dixon, A S L Tang, P D Wolf, et al, "Improved defibrillation thresholds with large contoured epicardial electrodes and biphasic waveforms," Circulation, vol. 76 #5, pp. 1176-1184, Nov. 1987.
Kugelberg, Jan. "Ventricular Defibrillation: a New Aspect", Acta Chirurgica Scandinavica, Supp. 372, Stockholm, 1967.
H A Blair, "On the intensity-time relations for stimulation by electric currents," J Gen Physiol., vol. 15, pp. 709-729, 1932.

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