Method for checking isolation between titration and electrochemi

Chemistry: electrical and wave energy – Processes and products

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204195R, 204195P, 204195T, 324 51, G01N 2744, G01N 2746, G01R 3100

Patent

active

041705238

ABSTRACT:
A method of checking the electrical isolation provided by a gas permeable membrane for a carbon dioxide sensor in an analyzer for simultaneously measuring the carbon dioxide and chloride content of a blood sample as it reacts with a reagent in a sample cell. The method involves actuating the carbon dioxide sensor during its normal "off-time" and measuring any signal generated thereby while a coulometric generator in the analyzer is initially activated to titrate to a repeatable initial value any chloride present in the reagent alone. Any signal generated by the sensor above a predetermined value is indicative of a defective membrane and may be utilized to inhibit further operation of the analyzer.

REFERENCES:
patent: 3661748 (1972-05-01), Blackmer
patent: 3718568 (1973-02-01), Neuwelt
patent: 3719576 (1973-03-01), Macur
patent: 4003705 (1977-01-01), Buzza et al.

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