Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-05-27
2000-10-03
McKane, Joseph K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548566, A61K 3140, A61K 31402, A61P 3104, A61P 3140, C07D20709
Patent
active
061274003
ABSTRACT:
This invention provides a novel and useful purification step in the manufacture of a diamine pyrrolidine side chain intermediate for a quinolone antibiotic that allows production of the antibiotic in significantly greater yields and at lower costs than was previously possible. Salts, procedures and processes for preparing them, including the salt disclosed in Formula A-1, below, are also disclosed. ##STR1##
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McKane Joseph K.
Oswecki Jane C.
Pharmacia & Upjohn Company
Wootton Thomas A.
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