Carbapenem antibacterial compounds, compositions containing such

Details Carbapenem antibacterial compounds, compositions containing such Carbapenem antibacterial compounds, compositions containing such

1997-04-08

1998-05-26

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514210, C07D48704, A61K 31395

Patent

active

057567255

ABSTRACT:
The present invention relates to carbapenem antibacterial agents in which the carbapenem nucleus is substituted at the 2-position with a naphthosultam linked through a CH.sub.2 group. The naphthosultam is further substituted with various substituent groups including at least one cationic group. The compounds are represented by formula I: ##STR1## Pharmaceutical compositions and methods of use are also included.

REFERENCES:
patent: 5034384 (1991-07-01), Greenlee et al.
patent: 5336674 (1994-08-01), Dininno et al.

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