Pharmaceutical compositions of botulinum toxin or botulinum neur

Details Pharmaceutical compositions of botulinum toxin or botulinum neur Pharmaceutical compositions of botulinum toxin or botulinum neur

1996-03-27

1998-05-26

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 530350, 530363, 530364, 530825, A61K 3800, C07K 100

Patent

active

057564680

ABSTRACT:
Lyophilized pharmaceutical compositions containing botulinum toxin or botulinum neurotoxin and effective amounts of trehalose and methionine have a shelf life of up to 4 months or more at room temperature and above.

REFERENCES:
patent: 5512547 (1996-04-01), Johnson et al.
Goodnough et al, Applied & Environmental Microbiology, vol. 58, No. 10, pp. 3426-3428, 1992.
Schantz & Johnson, "Properties and Use of Botulinum Toxin and Other Microbial Neurotoxins in Medicine", Mar. 1992, pp. 80-99.
Schantz & Johnson, "Preparation and Characterization of Botulinum Toxin Type A for Human Treatment", vol. 25, pp. 41-49, 94.
Goodnough & Johnson, "Stabilization of Clostridium Botulinum Neurotoxin During Lyophilization", Applied & Environmental Microbiology, Oct. 1992, pp. 3426-3428.

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