Process for the preparation of N-(2-chlorobenzyl)-2-(2-thienyl)

Details Process for the preparation of N-(2-chlorobenzyl)-2-(2-thienyl) Process for the preparation of N-(2-chlorobenzyl)-2-(2-thienyl)

1988-11-23

1989-10-10

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D33312

Patent

active

048733431

ABSTRACT:
In the process according to the invention 2-thiophene acetonitrile is reacted with 2-chlorobenzylamine and hydrogen in the presence of a hydrogenation catalyst.
The product obtained is a chemical intermediate useful in the pharmaceutical industry.

REFERENCES:
patent: 4458086 (1984-07-01), Chekroun et al.
Campaigne, E. and Walter C. McCarthy, "3-Substituted Thiophenes, VIII, 3-Thienylalkylamines", Journal of the American Chemical Society, vol. 76, No. 17, Sep. 9, 1954, pp. 4466-4468.

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