Retard form of pharmaceuticals with insoluble porous diffusion c

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424 20, 424 21, 424 22, 424 37, A61K 948, A61K 952

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active

043615465

ABSTRACT:
A pharmaceutical dosage unit retard form having a constant, pH-independent release rate of active ingredient, consisting of a core comprising an active ingredient, and a semi-permeable diffusion coating over the core, were the coating consists of a water-insoluble film-former, a water-soluble polymer and eventually an acid-insoluble polymer incorporated therein.

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Spitael et al., Pharmazeutische Industrie 39(5): 502-505 (1977) Factors Affecting the Dissolution Rate of Enterig Coatings.

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