Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1995-02-06
1996-09-03
Weimar, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530350, A61K 3800, C07K 700, C07K 710
Patent
active
055525245
ABSTRACT:
The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
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Zhang, et al., "Positional cloning of the mouse obese gene and its human homologue", Nature, 372:1, 425-432 (Dec. 1, 1994).
Rink, "In search of a satiety factor", Nature, 372:1, 406-407 (Dec. 1, 1994).
Flam, "Obesity Gene Discovery May Help Solve Weighty Problem", Science, 266, 1477-1478 (Dec. 2, 1994).
Marx, "Obesity Gene Discovery May Help Solve Weighty Problem", Science, 266, 1477-1478 (Dec. 2, 1994).
Basinski Margret B.
DiMarchi Richard D.
Heath, Jr. William F.
Schoner Brigitte E.
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Marshall S. G.
Weimar Elizabeth C.
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