Synthesis of 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythro

Details Synthesis of 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythro Synthesis of 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythro

1997-07-11

1999-02-09

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 71, 536 73, 536 74, 536 75, C07H 1708

Patent

active

058696296

ABSTRACT:
The preparation of azitromycin dihydrate from 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12-hydrogenorthoborate, obtained by a step by step process starting from 9-deoxo-6-deoxy-6,9-epoxy-9,9a-dihydro-9a-azahomoerythromycin A is a process which takes place under mild conditions and with good yields.

REFERENCES:
patent: 4328324 (1982-05-01), Kock et al.
patent: 4328334 (1982-05-01), Kobrehel et al.
patent: 4517359 (1985-05-01), Kobrehel et al.

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