Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-11-05
1999-02-09
Ulm, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
435 691, 4352523, 4353201, 536 235, C07K 14705, C12N 1512
Patent
active
058696121
ABSTRACT:
The invention concerns new tumor necrosis factor receptor associated factors, designated TRAF. The new factors are capable of specific association with the intracellular domain of the type 2 TNF receptor (TNF-R2), and are involved in the mediation of TNF biological activities.
REFERENCES:
patent: 4861587 (1989-08-01), Urbaschek et al.
Pharmacia Catalog pp. 133, 142-143 (1994).
Clonetech Catalog pp. 19, 192-194 (1994).
Berg, J., "Zinc Fingers and Other Metal-Binding Domains" Journal of Biological Chemistry 265(12):6513-6516 (1990).
Beutler, B. and Cerami, A., "Tumor necrosis, cachexia, shock, and inflammation: a common mediator" Ann. Rev. Biochem. 57:505-518 (1988).
Blake et al., "The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif" Oncogene 6:653-657 (1991).
Brockhaus et al., "Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies" Proc. Natl. Acad. Sci. USA 87:3127-3131 (1990).
Chan et al., "Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro Autoantigen" J. Clin. Invest. 87:68-76 (1991).
Cheng et al., "Involvement of CRAF1, a relative of TRAF, in CD40 signaling" Science 267(8):1494-1498 (1995).
Chevray et al., "Protein interaction cloning in yeast: identification of mammalian proteins that react with the Leucine Zipper of June" Proc. Natl. Acad. Sci. USA 89:5789-5793 (1992).
Chien et al., "The Two-Hybrid System: A method to identify and clone genes for proteins that interact with a protein of interest" Proc. Natl. Acad. Sci. USA 88:9578-9582 (1991).
Deng et al., "COP1, an arabidopsis regulatory gene, encodes a protein with both a zinc-binding motif and a G, homologous domain" Cell 71:791-801 (1992).
Driscoll and Williams, "Two divergently transcribed genes of dictyostelium discoideum are cyclic AMP-inducible and coregulated during development" Molecular & Cellular Biology 7(12):4482-4489 (1987).
Durfee et al., "The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit" Genes and Development 7(4):555-569 (1993).
Engelmann et al., "Antibodies to a Soluble Form of a Tumor Necrosis Factor (TNF) Receptor Have TNF-like Activity" Journal of Biological Chemistry 265(24):14497-14504 (1990).
Espevik et al., "Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor" Journal of Experimental Medicine 171:415-426 (1990).
Fields and Song, "A novel genetic system to detect-protein-protein interactions" Nature 340:245-246 (1989).
Fiers, W., "Tumor necrosis factor characterization at the molecular, cellular and In Vivro level" FEBS Letters 285(2):199-212 (1991).
Freemont et al., "A novel cysteine-rich sequence motif" Cell 64:483-484 (1991).
Goeddel et al., "TNF receptor signal transduction" Keystone Symposium on Hematopoiesis, Breckenridge, Colorado, Jan.4-11, 1994 (Abstract only) Supplement 0 (Supp 0(18 Pt A) :A011 (1994).
Goeddel et al., "Tumor Necrosis Factors: Gene Structure and Biological Activities" Cold Spring Harbor Symposia on Quantitative Biology LI:597-609 (1986).
Goodwin et al., "Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor" Molecular & Cellular Biology 11:3020-3026 (1991).
Gray et al., "Cloning and Expression of cDNA for Human Lymphotoxin, a Lymphokine with Tumor Necrosis Activity" Nature 312:721-724 (1984).
Haupt et al., "Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E.mu.-myc transgenic mice" Cell 65:753-763 (1991).
Hohmann et al., "Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kB" Journal of Biological Chemistry 265:22409-22417 (1990).
Hohmann et al., "Two different cell types have different major receptors for human tumor necrosis factor (TNF alpha)" Journal of Biological Chemistry 264(25): 14927-14934 (1989).
Hu et al., "A novel RING finger protein interacts with the cytoplasmic domain of CD40" Journal of Biological Chemistry 269(48):30069-30072 (1994).
Inoue et al., "Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a ring finger protein" Proc. Natl. Acad. Sci. USA 90:11117-11121 (1993).
Itoh et al., "Protein heterogenity in the human Ro/SSA ribonucleoproteins" J. Clin. Invest. 87:177-186 (1991).
Jones et al., "The saccharomyces cerevisiae RAD18 gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence" Nucl. Acids Res. 16(14):7119-7131 (1988).
Kohno et al., "A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor" Proc. Natl. Acad. Sci. USA 87:8331-8335 (1990).
Landschulz et al., "The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins" Science 204:1759-1764 (1988).
Lenardo and Baltimore, "NF-kB: A pleiotropic mediator of inducible and tissue-specific gene control" Cell 58:227-229 (1989).
Lewis et al., "Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific" Proc. Natl. Acad. Sci. USA 88:2830-2834 (1991).
Loetscher et al., "Molecular Cloning and Expression of the Human 55 kd Tumor Necrosis Factor Receptor" Cell 61:351-359 (Apr. 20, 1990).
Mardon and Page, "The sex-determining region of the mouse Y chromosome encodes a protein with a highly acidic domain and 13 zinc fingers" Cell 56:765-770 (1989).
Miller et al., "Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus Oocytes" EMBO Journal 4(6):1609-1614 (1985).
Miyatake et al., "Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes" EMBO Journal 4:2561-2568 (1985).
Mosialos et al., "The Epstein-Barr virus transforming LMP1 engages signaling proteins for the tumor necrosis factor receptor family" Cell 80:389-399 (1995).
Naume, B. et al., "Involvement of the 55- and 75-kDa tumor necrosis factor receptors in the generation of lymphokine-activated killer cell activity and proliferation of natural killer cells" J. Immunol. 146:3035-3048 (1991).
Neta et al., "Comparison of the In Vivo effects of rIL-1 and rTNF in radioprotection, induction of CSF and of acute phase reactants" Fed. Proc. (Abstract) 46(4):1200 (1987).
Neta et al., "Interdependence of the radioprotective effects of human recombinant interleukin 1.alpha., tumor necrosis factor .alpha., granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor" J. Immunol. 140(1):108-111 (1988).
Neta et al., "Interleukin 1 is a radioprotector" J. Immunol. 136(7):2483-2485 (Apr. 1, 1986).
Nietfeld et al., "Second-order repeats in xenopus laevis finger proteins" J. Mol. Bil. 208:639-659 (1989).
Nophar et al., "Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor" EMBO Journal 9:3269-3278 (1990).
Old, L.J., "Tumor Necrosis Factor" Sci. Am. 258(5):59-75 (1988).
Opipari et al., "The A20 cDNA induced by tumor necrosis factor .alpha. encodes a Novel type of zinc finger protein" Journal of Biological Chemistry 265:14705-14708 (1990).
Patarca et al., "rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1" Proc. Natl. Acad. Sci. USA 85:2733-2737 (1988).
Pennica et al., "Human Tumour Necrosis Factor: Precursor Structure, Expression and Homology to Lymphotoxin" Nature 312:724-729 (1984).
Reddy et al., "A novel zinc finger coiled-coil domain in a family of nuclear proteins" Trends Biochem. Sci. 17:344-345 (1992).
Rothe et al., "A novel famly of putative signal transducers associated w
Goeddel David V.
Rothe Mike
Dreger Ginger R.
Genetech, Inc.
Ulm John
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