Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-03-11
1999-02-09
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514259, 514278, 514323, 544284, 544373, 546 17, 546201, A61K 31495, C07D40112, C07D40312, C07D47110
Patent
active
058694897
ABSTRACT:
Disclosed are Substituted azacycles of formula I ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.
REFERENCES:
Frossard et al, Life Sciences, 49, pp. 1941-1953, 1991.
Maccoss Malcolm
Qi Hongbo
Shah Shrenik K.
Bernhardt Emily
Billups Richard C.
Merck & Co. , Inc.
Panzer Curtis C.
Rose David L.
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