Solid depot drug form

Details Solid depot drug form Solid depot drug form

1993-09-23

1996-09-03

Mullis, Jeffrey C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424486, 424488, A61K 920

Patent

active

055521592

ABSTRACT:
A solid depot drug form produced by melt extrusion at from 50.degree. to 200.degree. C. and continuous shaping of a mixture of from 0.1 to 70% by weight, based on the finished depot form, of a pharmaceutical active ingredient with a polymer melt of the following composition:

REFERENCES:
patent: 2987445 (1961-06-01), Levesque
patent: 3432592 (1969-03-01), Speiser
patent: 4548990 (1985-10-01), Mueller et al.
patent: 4647599 (1987-03-01), Bezzegh et al.
patent: 4708874 (1987-11-01), De Haan et al.
patent: 4784858 (1988-11-01), Ventouras
patent: 4801460 (1989-01-01), Goertz et al.
patent: 4837032 (1989-06-01), Ortega
patent: 4996065 (1991-02-01), Van de Walle
Rubin "Injection Molding", Encyclopedia of Polymer Science and Engineering, vol. 8, pp. 102-138.

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