Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1998-03-23
1999-02-09
Witz, Jean C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
540145, C12P 2106, C07B 4700
Patent
active
058692797
ABSTRACT:
Hemin-like porphyrins can be prepared from chlorophylls and hemin, which may be used as intermediates to form functionally active porphyroproteins. The porphyrins can be reacted with apoproteins in vitro or added to a cell culture and combined intracellularly with apoproteins to form functionally active porphyroproteins.
REFERENCES:
patent: 5028588 (1991-07-01), Hoffman et al.
Fanelli et al., "Studies on the Structure of Hemoglobin: Physicochemical Properties of Human Globin", Biochemica Biophysica Acta, vol. 30, No. 3, (1958) pp. 608-616.
Siefermann-Harms et al., "Reassembly of solubilized chlorophyll-protein complexes in proteolipid particles comparison of monogalactosyldiacygyl and two phosphollpids", Biochim. Biophys. Acta (1987) 892:303-331.
Brady et al., General Chemisty, 2nd. edition. (Wiley: New York) (1978) pp. 362-363.
Antonini et al., "Studies on the structure of hemoglobin III. Physicochemical properties of reconstituted hemoglobins", Biochim. Biophys. Acta (1964) vol. 79, pp. 284-292.
Tavill et al., "The role of heme in the synthesis and assembly of hemolglobin", J. Biol. Chem. (1968) vol. 243 (19), pp. 4987-4999.
Kaphart, "Chlorophyll Derivatives--Their Chemistry, Commercial Preparation and Uses", Econ. Botany vol. 88 No. 21 (1955) pp. 3-38.
Dougherty et al., Journal of the American Chemical Society:, vol. 88 No. 21, (1996) pp. 5307-5308.
Smith et al., "New Efficient Total Syntheses of Derivatives of Protoporphyrin-1X", Journal of Heterocycylic Chemistry, vol. 20, No. 5, (1983) pp. 1383-1388.
Smith et al., "Syntheses of Isomers of Protoporphyrin-1X: With Permuted Propionic Side-Chains", Journal of Heterocyclic Chemistry, vol. 22, No. 4, (1985) pp. 1041-1044.
Hanley Susan
Witz Jean C.
LandOfFree
Modified porphyroproteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modified porphyroproteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified porphyroproteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1947732