Continuous bovine beta cell line

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435240, C12P 2104, C12N 500

Patent

active

044775679

ABSTRACT:
A new cell line which is morphologically very similar to the beta cell of the Islets of Langerhans is obtained by transformation of pancreatic bovine cells. The transformed cells contain the diploid number of chromosomes for the bovine species and produce insulin which may be extracted.

REFERENCES:
patent: 4225671 (1980-09-01), Puchinger
Chick et al.--Science, vol. 187, (Mar. 7, 1975), pp. 847 & 848.
Chick et al.--Endocrinology, vol. 92, No. 1, (1973), pp. 212, 213, 216-218.

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