Molecular detection apparatus and method using optical waveguide

Details Molecular detection apparatus and method using optical waveguide Molecular detection apparatus and method using optical waveguide

Filed on

1996-04-17

Date issued

1997-09-23

Examiner

Healy, Brian

Patent Class

Optical waveguides

SubClass

Optical waveguide sensor

Other Related Categories

385129, 385130, 385131, 385 14, 385147, 356128, G02B 600, G01N 2141

Type

Patent

Status

active

Patent number

056713037

Description

ABSTRACT:
A target molecule at a binding site is detected using an optical waveguide having a surface proximate to the binding site, and a waveguide detector coupled to the optical waveguide. An incident light beam is applied to the binding site along an axis transverse to the surface of the optical waveguide. The incident light beam impinges an optical indicator associated with the target molecule to form secondary light which is coupled into the optical waveguide. The secondary light is detected by the waveguide detector to thereby detect the target molecule.

REFERENCES:
patent: 4815843 (1989-03-01), Tiefenthaler et al.
patent: 5120131 (1992-06-01), Lukosz
patent: 5194393 (1993-03-01), Hugl et al.
patent: 5344784 (1994-09-01), Attridge
patent: 5439647 (1995-08-01), Saini
patent: 5455178 (1995-10-01), Fattinger
patent: 5479260 (1995-12-01), Fattinger
patent: 5492840 (1996-02-01), Malmqvist et al.

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