Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Hydrocarbon doai
Patent
1995-06-30
1997-09-23
Weddington, Kevin E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Hydrocarbon doai
A61K 31015
Patent
active
056705492
ABSTRACT:
A method for preventing acetaminophen toxicity in a mammal is provided. An acetaminophen toxicity inhibiting amount of beta-carotene is administered before, simultaneously with, after, or any combination thereof, administering acetaminophen to the mammal. Methods for reducing acetaminophen toxicity in a mammal in need of such treatment and for increasing the maximum amount of acetaminophen that can be administered to a mammal without the mammal exhibiting acetaminophen toxicity are also provided. Acetaminophen toxicity reducing amounts and acetaminophen toxicity preventing amounts, respectively, are administered. In another embodiment, a non-steroidal analgesic and anti-inflammatory composition of acetaminophen and an acetaminophen toxicity preventing amount of beta-carotene is provided.
REFERENCES:
patent: 4159340 (1979-06-01), Szmuszkovicz
patent: 4307073 (1981-12-01), Nelson
patent: 4314989 (1982-02-01), Rosen et al.
patent: 4435427 (1984-03-01), Hoppe et al.
patent: 4491547 (1985-01-01), Seifter et al.
patent: 4520134 (1985-05-01), Rosen
patent: 4681897 (1987-07-01), Brand
patent: 4713398 (1987-12-01), Nonomura
patent: 4730007 (1988-03-01), Ehrenpreis
patent: 4820523 (1989-04-01), Shtohryn et al.
patent: 4868114 (1989-09-01), Nagasawa et al.
patent: 5260340 (1993-11-01), Baranowitz et al.
Ademoyero et al. Chemical Abstracts.
Oshima et al. Chemical Abstracts.
Chemical Abstracts 174463s, Ademoyero et al., 98:21, Sep. 27, 1983.
Chemical Abstracts 56093, Shoyakugaku Zasshi, 102:7, 5, Dec. 5, 1984.
McLean et al., Biochemical Pharmacology 24:37-42 (1975).
R.E. Bagdon et al., Toxicology and Applied Pharmacology 2:225-236 (1960).
Tapan K. Basu et al., J. Clin. Biochem. Nutr. 3:95-102 (1987).
I.A. Donatus, Biochemical Pharmacology 39(12):1869-1875 (1990).
J.C. Drummond et al., J. Physiol. 82:75-78 (1934).
Kenjiro Wake Intl. Review of Cytology 66(303):328-329 (1980).
93:10899r Chem Abstracts (1980).
98:174463s Chem Abstracts (1983).
108:36579h Chem Abstracts (1988).
109:224531f Chem Abstracts (1988).
111:19325s Chem Abstracts (1989).
114:214526x Chem Abstracts (1991).
114:136070c Chem Abstracts (1991).
M. R. Clemens et al., Zeitschrift fur Ernahrungswissenschaft 31:110-120 (1992).
Baranowitz Steven
Maderson Paul F.
LandOfFree
Prevention and amelioration of liver toxicity with beta-carotene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prevention and amelioration of liver toxicity with beta-carotene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prevention and amelioration of liver toxicity with beta-carotene will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1938857