Piperazine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514218, 514252, 514254, 514255, 540575, 544121, 544357, 544360, 544364, 544367, 544373, 544376, 544379, 544385, 544387, 544388, 544391, 544403, 548495, 549 58, 560 27, 560 28, A61K 31495, A61K 3155, C07D40314, C07D40114

Patent

active

056705050

ABSTRACT:
A piperazine compound of the formula: ##STR1## wherein: X is carbonyl or sulfonyl;
Y is a direct bond or lower alkylene; and
R.sub.1, R.sub.2, R.sub.3, R.sub.4 are as defined herein. The compounds are advantageously used as Tachykinin antagonists in the treatment of respiratory diseases, ophthalmic diseases and inflammatory diseases, for example.

REFERENCES:
patent: 4598079 (1986-07-01), Beyerle et al.

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