Porous particle aggregate and method therefor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 60, 514 57, 536 56, 536102, 536103, 536114, 5361231, 536124, 530350, A61K 31715, C07H 100, C08B 3000, C08B 1100

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056704909

ABSTRACT:
A porous aggregate having a high intraaggregate reticular volume for releasable containment of functional substances is described. The porous aggregates comprise discrete particles, preferably starch granules, bound together at least at their points of contact in the aggregates. The surfaces of the discrete particles cooperate to define an intraaggregate reticulate volume. The porous aggregate composition of this invention finds use as a high capacity carrier of functional substances for a wide variety of applications, in which the functional substance is released from the aggregate composition under the influence of mechanical compression/disintegration, by degradation or dissolution of the binder and/or particulate components, or by diffusion from the porous surface.

REFERENCES:
patent: 4144079 (1979-03-01), Smith
patent: 4159982 (1979-07-01), Hermansson
patent: 4549909 (1985-10-01), Samuel et al.
patent: 4612284 (1986-09-01), Pickens et al.
patent: 4985082 (1991-01-01), Whistler
patent: 5051133 (1991-09-01), Nagai et al.
patent: 5346892 (1994-09-01), Fitt et al.

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