Cephalosporin antibiotic

Details Cephalosporin antibiotic Cephalosporin antibiotic

1982-08-16

1984-08-21

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, C07D50146

Patent

active

044670869

ABSTRACT:
(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamid o]-3-(1-pyridiniummethyl) ceph-3-em-4-carboxylate in the form of a crystalline bishydrochloride.
The bishydrochloride has a well defined crystalline structure and exhibits good stability in storage. The bishydrochloride exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with .beta.-lactam antibiotics.

REFERENCES:
patent: 4258041 (1981-03-01), O'Callaghan et al.

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