Polyene compounds useful in the treatment of allergic responses

Details Polyene compounds useful in the treatment of allergic responses Polyene compounds useful in the treatment of allergic responses

1985-10-16

1986-08-12

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ether doai

514731, A61K 3105, A61K 31075

Patent

active

046056750

ABSTRACT:
Polyene compounds represented by the formula ##STR1## in which R is H or an alkyl group of from 1 to 5 carbon atoms, R.sub.1 is H, lower alkyl of from 1 to 8 carbon atoms or aralkyl, and the pharmaceutically acceptable salts thereof.
The foregoing compounds have been found active in regulating phospholipases and as such possess therapeutic value in the treatment of inflammatory conditions.

REFERENCES:
Dawson et al. J. Med. Chem. (1981) 24 1214.

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