Method for percutaneously administering metoclopramide

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514785, 514969, 604290, 604304, 604896, A61K 31165, A61K 4700

Patent

active

046056700

ABSTRACT:
A method of percutaneously administering metoclopramide which comprises applying to the skin of a mammal metoclopramide in a carrier system which comprises at least one adjuvant and at least one solvent. The adjuvant is a monovalent alcohol ester of an aliphatic monocarboxylic acid or an aliphatic monoalcohol. The solvent is a pyrrolidone-type compound. Mixtures can also be used.

REFERENCES:
patent: 3964482 (1976-06-01), Gerstel et al.
patent: 4411893 (1983-10-01), Johnson et al.
patent: 4444762 (1984-04-01), Rajadhyaksha

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