Large-liposome agglutination reagent and method

Details Large-liposome agglutination reagent and method Large-liposome agglutination reagent and method

1983-07-27

1986-08-12

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving diffusion or migration of antigen or antibody

Through a gel

436528, 436529, 436535, 436800, 436805, 436819, 436829, 264 46, 4284022, G01N 33544, G01N 33571, B32B 516, B01J 1300

Patent

active

046056300

ABSTRACT:
An agglutination assay reagent and method. The reagent is composed of liposomes predominantly in the 1 to 20 micron diameter size range. Each liposome has a surface array of laterally mobile ligand molecules, at a surface concentration adapted to produce reagent agglutination within about 5 minutes, when the reagent is incubated at room temperature with a multivalent ligand-binding analyte. A dye in the liposomes allows such agglutination to be visualized easily without magnification.

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