Synthesis of 1,3-dideoxy-3-fluoronojirimycin

Details Synthesis of 1,3-dideoxy-3-fluoronojirimycin Synthesis of 1,3-dideoxy-3-fluoronojirimycin

1992-03-02

1993-06-08

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546116, 546219, 546220, C07D491056, C07D21142

Patent

active

052181219

ABSTRACT:
Novel compounds represented by the formula: ##STR1## wherein R represents hydrogen, optionally substituted alkyl radicals having from 1 to about 10 carbon atoms, optionally substituted alkenyl radicals having from 1 to about 10 carbon atoms, optionally substituted aryl, alkaryl and aralkyl radicals having from about 6 to about 16 carbon atoms and optionally substituted acyl and acyloxy radicals having from about 1 to about 10 carbon atoms, manifest glycosidase inhibition activity.

REFERENCES:
patent: 4348402 (1982-09-01), Kinast et al.
M navu et al., J. Org. Chem., 41, 1831 (1976).
David et al., Tetrahedron, 41, (4), 643 (1985).
Tsuda et al., Chem. Pharm. Bull., 31(5), 1612 (1983).
Boshagan et al., Carbohydrate Research, 164, 141 (1987).

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