Compounds having antihypertensive properties

Details Compounds having antihypertensive properties Compounds having antihypertensive properties

1990-11-15

1993-06-08

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514187, 514255, 514269, 514353, 514369, 514372, 514427, 514445, 546308, 546309, 546153, 546155, 546156, 544298, 544299, 544301, 544303, 544408, 548541, 548542, 548544, 548545, 548546, 564167, A61K 3144, C07D21302

Patent

active

052179826

ABSTRACT:
This invention relates to compounds which are derivatives of cyclopentane which are useful as antihypertensive agents, to pharmaceutical compositions including such compounds, and to their use in treating hypertension.

REFERENCES:
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patent: 4098903 (1978-07-01), Fountain et al.
patent: 4148913 (1979-04-01), Szmuszkovicz
patent: 4156015 (1979-05-01), Szmuszkovicz
patent: 4159340 (1979-06-01), Szmuszkovicz
patent: 4204003 (1980-05-01), Szmuszkovicz
Houston et al, J. Med. Chem., 1985, vol. 28, No. 4, 467-477.
Bowman, et al., Synthesis of Flufenamic Acid Metabolites I and II and Other N-Arylanthranilic Acids; J. Chem. Soc. Perkin Trans. 1, (1), 1-4 (1973).
Synthesis of 3-Deazaclitocine [2-amino-3-nitro-4-(.beta.-D-ribofuranosylamino)pyridine] as Cytotoxic Agent; Nucleosides & Nucleotides, 10 (1-3), 543-545 (1991).
Baxter, et al., Synthesis and Biological Activity of Carbocyclic clitocine; Nucleosides & Nucleotides, 10 (1-3), 393-396 (1991).

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