Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1991-03-13
1993-06-08
Lacey, David L.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
435 7021, 4351722, 5303872, 5303873, 53038835, 424 858, 424 86, C12N 520, C07K 1528, A61K 39395
Patent
active
052178951
ABSTRACT:
Disclosed are immunologically active polypeptides, preferably antibodies or antibody fragments, and most preferably monoclonal antibodies, which are reactive with idiotypes of antibodies to human lymphocyte T4 protein and are reactive with the HIV virion in a manner allowing for in vitro and in vivo neutralization of HIV infectivity and detection of HIV particles in biological fluids. Presently preferred embodiments comprise monoclonal anti-monoclonal-anti-human lymphocyte T4 antibodies produced by new murine hybridoma cell lines JT4C8, JT4C12, JT4C16, JT1-1F3, JT1-1F3-E5, JT1-1D7 and JT2-N15. Also disclosed are active and passave vaccination procedures.
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Budens Robert D.
Lacey David L.
Nissin Shokuhin Kabushiki Kaisha
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