Process for production of (R) methylsuccinic acid from squalene

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435244, 435255, 435923, C12P 744, C12N 138

Patent

active

052178870

ABSTRACT:
A process for the production of methylsuccinic acid represented by the formula (I): ##STR1## wherein the symbol * represents an asymmetric carbon atom, comprising the steps of culturing Candida in a medium containing squalene and producing methylsuccinic acid.

REFERENCES:
patent: 3843466 (1974-10-01), Akabori et al.
Mueller et al, Helv. Chim. Acta 69: 1829-32 (1986).

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