Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1987-03-17
1987-12-01
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514562, 514535, 560 43, 560 16, 562432, 562426, 562455, A61K 31195
Patent
active
047105151
ABSTRACT:
Novel compounds which are 2,6-di-tertiary-butylphenols substituted in the 4 position by an acylaminophenyl group, which acylaminophenyl group is substituted by a moiety which includes a carboxyl group, are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents.
REFERENCES:
patent: 4055653 (1977-10-01), Offermanns et al.
patent: 4094857 (1978-06-01), Wolfe
patent: 4153728 (1979-05-01), Wolff
patent: 4172151 (1979-10-01), Moore
Bailey et al., Ann Rpts. Med. Chem., vol. 17, pp. 203-207 (1982).
Samuelsson, Science, vol. 220, pp. 568-575 (1983).
Kirk Alan R.
Scherrer Robert A.
Reamer James H.
Riker Laboratories Inc.
Sell Donald M.
Smith James A.
Sprague Robert W.
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