3-heteroarylalkyl-4-quinazolinones

Details 3-heteroarylalkyl-4-quinazolinones 3-heteroarylalkyl-4-quinazolinones

1985-11-04

1987-12-01

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544284, A61K 31505, C07D40306

Patent

active

047105020

ABSTRACT:
Novel 3-heteroarylalkyl-4-quinazolinones which are useful as inhibitors of thromboxane synthetase and/or as antihypertensive agents in the treatment of hypertension and myocardial ischemia.

REFERENCES:
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patent: 3454574 (1969-07-01), Keck et al.
patent: 3557117 (1971-01-01), Shetty
patent: 3558610 (1971-01-01), Breuer et al.
patent: 4335127 (1982-06-01), Vandenberk et al.
Kishor, et al., "Chemical Abstracts", vol. 62, 1965, col. 4471c.
Hideg et al., "Chemical Abstracts", vol. 74, 1971, col. 88041a.
Vorga, et al., "Chemical Abstracts", vol. 84, 1976, col. 84:123b.
Hideg, K., et al., "Hung. Teljes 229, 2,3-Disubstituted-Quinazolines" in Chem. Abstracts, 74(17), p. 445, 88041a (1971).

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