Cholesterol lowering/antioxidant nitroxides

Details Cholesterol lowering/antioxidant nitroxides Cholesterol lowering/antioxidant nitroxides

1993-04-16

1995-02-21

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20746, A61K 3140

Patent

active

053917650

ABSTRACT:
The present invention relates to novel nitroxides which are useful for cholesterol lowering and as antioxidant agents. Also provided is a process for preparing the nitroxides of the present invention, pharmaceutical compositions, and a method of treating or inhibiting hypercholesterolemia, hyperlipidemia, atherosclerosis, and LDL oxidation which comprises administering to birds and mammals, in need of such treatment an effective amount of a compound of the present invention.

REFERENCES:
patent: 5217992 (1993-06-01), Wright
Qureshi, A. A., "Dietary Tocotrienols . . . ", Am J Clin Nutr, 53, pp. 10425-10465, 1991.
A. A. Qureshi, "Lowering of Serum Cholesterol . . . ", Am J Clin Nutr, 53, pp. 10215-10265, 1991.
B. C. Pearce, "Hypercholesterolemic Activity . . . ", J. Med. Chem., 35, pp. 3595-3606, 1992.
Nutrition: An Integrated Approach, Ruth Pike, 1984, pp. 531-534.

Affiliated with

Also associated with

Rating

Cholesterol lowering/antioxidant nitroxides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cholesterol lowering/antioxidant nitroxides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cholesterol lowering/antioxidant nitroxides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1931508