Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1986-07-28
1987-12-01
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424468, 424469, 424470, 424489, 424490, A61K 950, A61K 928, A61K 926, A61K 922
Patent
active
047103841
ABSTRACT:
A tablet for oral adminstration of a sustained-release medication is formed by compressing microcapsules of the active principle. The microcapsules are of a size range between about 5 and 300 microns and comprise particles of active principle coated with a thin, flexible layer of sustained release material. The sustained-release material contains about 15-30% by weight thereof of plasticizer and is coated in an amount corresponding to 10-25% of the weight of the active material. Excipients causing disintegration of the tablet after administration can be uniformly mixed with the microcapsules prior to compression.
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