Pharmaceutical compositions containing 1,4-bis-(5'-nitroimidazol

Details Pharmaceutical compositions containing 1,4-bis-(5'-nitroimidazol Pharmaceutical compositions containing 1,4-bis-(5'-nitroimidazol

1974-12-20

1976-08-03

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 31495

Patent

active

039730190

ABSTRACT:
1,4-BIS-5'-NITROIMIDAZOLYL-2'-METHYLENE-IMINO) PIPERAZINES OF THE FORMULA ##SPC1##
In which R.sub.1 is hydrogen, methyl, ethyl or 2-hydroxyethyl and R.sub.2 is hydrogen or methyl, are prepared by reaction of 5-nitro-imidazolyl-2-aldehydes or the functional derivatives thereof with 1,4-diamino-piperazines. Pharmaceutical compositions containing these compounds for treating protozoal diseases and methods of treating protozoal diseases with these compounds are disclosed.

REFERENCES:
patent: 3752809 (1973-08-01), Rufer et al.

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