Transdermal flux enhancing compositions to treat hypertension, d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514212, 514221, 514350, 514671, 514557, 514560, 514729, 514546, 514946, 514947, 514866, 514784, 514785, 514788, 514255, 424449, A61K 3155, A61K 3144, A61K 3122, A61K 970

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active

053915488

ABSTRACT:
A transdermal flux enhancing pharmaceutical composition for transdermal administration to a human or lower animal subject comprising a safe and effective amount of a pharmacologically active compound or a prodrug thereof, an aqueous solvent system comprising from about 15 to 75% by volume of one or more water miscible solvents, and a penetration enhancer selected from certain 1-alkylazacycloheptan-2-ones and cis-olefin compounds of the formula

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